This meatloaf sandwich is a tasty treat, with juicy slices of homemade meatloaf tucked between soft bread. It’s simple, filling, and perfect for lunch!
Sometimes, I add a slice of cheese and a dollop of ketchup for an extra kick. Trust me, it tastes amazing! Who wouldn’t love a sandwich like this? 😊
Key Ingredients & Substitutions
Ground Beef: I recommend using 80/20 ground beef for the best flavor and moisture. If you’re looking for leaner options, ground turkey or chicken also works well!
Onions: Finely chopped onions add great flavor. If you’re not a fan of onions, you can skip them or substitute with onion powder for a milder taste.
Ketchup: This not only adds flavor but helps bind the meatloaf together. You can use barbecue sauce or even homemade tomato sauce if you want a different twist.
Bread Crumbs: Traditional bread crumbs are classic, but crushed crackers or oatmeal can work too. Use gluten-free options if needed!
Cheese: Provolone or mozzarella gives a nice melt. Feel free to swap in cheddar or pepper jack for a robust flavor hit!
How Do I Get My Meatloaf Sandwich to be Extra Juicy?
Cooking the meatloaf properly is key to a juicy sandwich. Here are some tips:
- Don’t overmix the meat mixture; this can make the loaf dense.
 - Let the meatloaf rest after baking. This helps the juices redistribute, keeping it moist when you slice it.
 - Use a meat thermometer to check that it hits 160°F (71°C). This way, it’s fully cooked but not overdone!
 - When grilling the sandwich, keep the heat moderate. This ensures the cheese melts properly without burning the bread.
 
By following these tips and using quality ingredients, you will have a delicious meatloaf sandwich that everyone will enjoy!

How to Make a Delicious Meatloaf Sandwich
Ingredients You’ll Need:
For the Meatloaf:
- 1 lb ground beef
 - 1/2 cup bread crumbs
 - 1/4 cup finely chopped onion
 - 1/4 cup ketchup (plus extra for topping)
 - 1 egg
 - 1/4 cup milk
 - 1 tsp Worcestershire sauce
 - 1/2 tsp garlic powder
 - 1/2 tsp salt
 - 1/4 tsp black pepper
 
For the Sandwich:
- 4 slices of bread (preferably white or sourdough)
 - 4 slices of cheese (such as provolone or mozzarella)
 - Butter (for grilling bread)
 
How Much Time Will You Need?
This recipe takes about 10 minutes of prep time, 55-60 minutes to bake the meatloaf, and then about 10 minutes to assemble and grill the sandwiches. Total time is around 1 hour and 20 minutes to enjoy a delicious meatloaf sandwich!
Step-by-Step Instructions:
1. Prepare the Meatloaf:
Start by preheating your oven to 350°F (175°C). In a large bowl, combine the ground beef, bread crumbs, chopped onion, ketchup, egg, milk, Worcestershire sauce, garlic powder, salt, and pepper. Use your hands or a spoon to mix it very gently until everything is just combined. Be careful not to overhandle it as this can make the meatloaf tough.
2. Shape and Bake the Meatloaf:
Take the mixed meatloaf ingredients and shape them into a loaf. Place this loaf into a small baking pan or a loaf pan. For a little extra flavor, spread a thin layer of ketchup on top of the meatloaf.
Now, pop it into the preheated oven and bake for about 55-60 minutes. You want it to reach an internal temperature of 160°F (71°C). Once done, let the meatloaf rest for about 10 minutes so the juices can settle before slicing.
3. Grill the Sandwiches:
While the meatloaf is resting, heat a skillet over medium heat and butter one side of each slice of bread. Grab two slices of bread and place them butter side down on the skillet. Add a slice of cheese on each piece, then layer on thick slices of the cooked meatloaf.
If you like, drizzle a bit more ketchup on top of the meatloaf slices for extra flavor. Add the other slices of bread on top, butter side up. Grill the sandwiches until the bread is golden brown and the cheese is nice and melty, about 3-4 minutes on each side.
4. Serve and Enjoy!
Once the sandwiches are grilled to perfection, remove them from the skillet. Slice them in half and serve warm. Enjoy your hearty meatloaf sandwich with your favorite sides!
Bon appétit! 😊
Can I Use Leftover Meatloaf for This Sandwich?
Absolutely! Leftover meatloaf is perfect for making sandwiches. Just slice it thickly and follow the same grilling instructions. It’s a great way to repurpose your dinner into a delicious lunch!
What Kind of Bread Works Best for Meatloaf Sandwiches?
Sourdough or white bread are excellent choices as they hold up well when grilling and have a nice texture. You can also use whole grain or rye for added flavor and nutrition if you prefer!
Can I Freeze the Meatloaf Before Cooking?
Yes, you can! Shape the meatloaf and tightly wrap it in plastic wrap, then place it in the freezer. Just make sure to thaw it in the fridge overnight before baking the next day for the best results.
How Do I Store Leftover Sandwiches?
Store leftover sandwiches in an airtight container in the fridge for up to 2 days. To reheat, warm them in a skillet over low heat, covering with a lid to help the cheese melt evenly without burning the bread.
